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Bioprocess Engineering. Edition No. 3

  • ID: 4850259
  • Book
  • 1220 Pages
  • Elsevier Science and Technology
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Bioprocess Engineering: Kinetics, Biosystems, Sustainability, and Reactor is a systematic and comprehensive textbook on bioprocess kinetics, molecular transformation, bioprocess systems, sustainability and reaction engineering. Dr. Shijie Liu reviews the relevant fundamentals of chemical kinetics, batch and continuous reactors, biochemistry, microbiology, molecular biology, reaction engineering, bioprocess systems engineering, introducing key principles that enable bioprocess engineers to engage in the analysis, optimization, selection of cultivation methods, design and consistent control over molecular biological and chemical transformations. The quantitative treatment of bioprocesses is the central theme in this text, while more advanced techniques and applications are covered with some depth. This text reflects powerful advances that are transforming the field, ranging from genetic sequencing to new techniques for producing proteins from recombinant DNA, from complex molecular regulation to interactive enzymes, from green chemistry to process stability and sustainability, from reactive and biohazard to process safety. It introduces techniques with broad applications to the conversion of renewable biomass, the production of chemicals, materials, pharmaceuticals, biologics, and commodities to medical applications such as tissue engineering and gene therapy; and for solving critical environmental problems. In addition to updated contents, the third edition presents the much improved treatise and fundamental principles on complex molecular transformations: solid catalysis (cooperative catalysis) and complex enzymatic catalysis. Real reactors and their analysis are also covered in this new edition.
  • Includes biological molecules and chemical reaction basics, cell biology and genetic engineering
  • Describes kinetics and catalysis at molecular and cellular levels, along with the principles of fermentation
  • Covers advanced topics and treatise in interactive enzyme and molecular regulations, also covering solid catalysis
  • Explores bioprocess kinetics, mass transfer effects, reactor analysis, control and design
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1. Introduction 2. An Overview of Biological Basics 3. An Overview of Chemical Reaction Analysis 4. Batch Reactor 5. Ideal Flow Reactors 6. Kinetic Theory and Reaction Kinetics 7. Enzymes 8. Chemical Reactions on Solid Surfaces 9. Cell Metabolism 10. Interactive Enzymes / Proteins 11. Molecular Regulation on Multifunctional Enzymes 12. How Cells Grow 13. Cell Cultivation 14. Evolution and Genetic Engineering 15. Sustainability: Humanity Perspective 15 Sustainability and Stability 17. Mass Transfer Effects: Immobilized and Heterogeneous Reaction Systems 18. Bioreactor Design and Operation 19. Combustion, Reactive Hazard and Bioprocess Safety 20. Nonideal Reactors 21. Bioprocess Kinetics Experimental Design

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Liu, Shijie
Dr. Shijie Liu is a professor of bioprocess engineering at the State University of New York - College of Environmental Science and Forestry (SUNY ESF), Syracuse, NY, USA. His contributions include volume averaging in porous media, kinetics of reactions on solid surfaces, cooperative adsorption theory, the theory of interactive enzymes, and the kinetic modeling of polyauxic growth / fermentation. Much of his childhood was spent in the country side of Sichuan Province in China, finished high school in 1978 from Luxi High School, in a little town just a few kilometers away from his home of birth. He graduated from Chengdu University of Science and Technology (now merged into Sichuan University) with a BS degree in Chemical Engineering in 1982. His early career started in the chemical industrial city of Lanzhou, China before moving to Canada. He obtained his PhD degree in Chemical Engineering from the University of Alberta in 1992 under Prof. Jacob H. Masliyah. Since then, he worked in the University of Alberta and Alberta Research Council before joining SUNY ESF in 2005. He has over 150 peer-reviewed publications today and maintains strong collaborations with colleagues in China from various universities. He taught a variety of courses including transport phenomena, numerical methods, mass transfer, chemical kinetics, pulp and paper technology, colloids and interfaces, chemical reaction engineering, bioreaction engineering, bioprocess kinetics and systems engineering, bioefinery processes, advanced biocatalysis, advanced bioprocess kinetics, and bioprocess engineering. Dr. Liu currently serves as the Editor-In-Chief of the Journal of Biobased Materials and Bioenergy, as well as the Editor-In-Chief of the Journal of Bioprocess Engineering and Biorefinery.
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